The inhibition of UBC13 expression and blockage of the DNMT1-CHFR-Aurora A pathway contribute to paclitaxel resistance in ovarian cancer

Paclitaxel is widely used as a first-line chemotherapeutic drug for patients with ovarian cancer and other solid cancers, but drug resistance occurs frequently, resulting in ovarian cancer still presenting as the highest lethality among all gynecological tumors. Here, using DIGE quantitative proteom...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, Xu, Feng, Yan, Wang, Xin-Yu, Zhang, Ya-Nan, Yuan, Chun-Nv, Zhang, Song-Fa, Shen, Yuan-Ming, Fu, Yun-Feng, Zhou, Cai-Yun, Li, Xiao, Cheng, Xiao-Dong, Lu, Wei-Guo, Xie, Xing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833742/
https://ncbi.nlm.nih.gov/pubmed/29367628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0137-x
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