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Molecular and physiological roles of the adaptor protein CARD9 in immunity

CARD9 is a caspase recruitment domain-containing signaling protein that plays a critical role in innate and adaptive immunity. It has been widely demonstrated that CARD9 adaptor allows pattern recognition receptors to induce NF-κB and MAPK activation, which initiates a “downstream” inflammation cyto...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Zhong, Xiaoming, Chen, Bin, Yang, Liang, Yang, Zhiwen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833731/
https://ncbi.nlm.nih.gov/pubmed/29352133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0084-6
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