Lrig1 is a haploinsufficient tumor suppressor gene in malignant glioma

Recently, a genome-wide association study showed that a single nucleotide polymorphism (SNP) —rs11706832—in intron 2 of the human LRIG1 (Leucine-rich repeats and immunoglobulin-like domains 1) gene is associated with susceptibility to glioma. However, the mechanism by which rs11706832 affects glioma...

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Bibliografiske detaljer
Udgivet i:Oncogenesis
Main Authors: Mao, Feng, Holmlund, Camilla, Faraz, Mahmood, Wang, Wanzhong, Bergenheim, Tommy, Kvarnbrink, Samuel, Johansson, Mikael, Henriksson, Roger, Hedman, Håkan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833707/
https://ncbi.nlm.nih.gov/pubmed/29391393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-017-0012-8
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