Glucocorticoids promote apoptosis of proinflammatory monocytes by inhibiting ERK activity

Glucocorticoids (GCs) are potent anti-inflammatory drugs whose mode of action is complex and still debatable. One likely cellular target of GCs are monocytes/macrophages. The role of GCs in monocyte survival is also debated. Although both granulocyte macrophage-colony stimulating factor (GM-CSF) and...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Achuthan, Adrian, Aslam, Ahmad S. M., Nguyen, Quyen, Lam, Pui-Yeng, Fleetwood, Andrew J., Frye, Ashlee T., Louis, Cynthia, Lee, Ming-Chin, Smith, Julia E., Cook, Andrew D., Olshansky, Moshe, Turner, Stephen J., Hamilton, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833693/
https://ncbi.nlm.nih.gov/pubmed/29449600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0332-4
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