Effect of Idalopirdine as Adjunct to Cholinesterase Inhibitors on Change in Cognition in Patients With Alzheimer Disease: Three Randomized Clinical Trials

IMPORTANCE: New therapeutic approaches for Alzheimer disease (AD) are needed. OBJECTIVE: To assess whether idalopirdine, a selective 5-hydroxytryptamine-6 receptor antagonist, is effective for symptomatic treatment of mild to moderate AD. DESIGN, SETTING, AND PARTICIPANTS: Three randomized clinical...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Atri, Alireza, Frölich, Lutz, Ballard, Clive, Tariot, Pierre N., Molinuevo, José Luis, Boneva, Neli, Windfeld, Kristian, Raket, Lars L., Cummings, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833662/
https://ncbi.nlm.nih.gov/pubmed/29318278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2017.20373
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