Association of LPA Variants With Aortic Stenosis: A Large-Scale Study Using Diagnostic and Procedural Codes From Electronic Health Records

IMPORTANCE: Elevated lipoprotein(a) levels are a risk factor for aortic stenosis (AS). However, a large-scale replication of associations between LPA variants and AS, their interactions with risk factors, and the effect of multiple risk alleles is not well established. OBJECTIVE: To replicate the as...

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Vydáno v:JAMA Cardiol
Hlavní autoři: Chen, Hao Yu, Dufresne, Line, Burr, Hannah, Ambikkumar, Athithan, Yasui, Niko, Luk, Kevin, Ranatunga, Dilrini K., Whitmer, Rachel A., Lathrop, Mark, Engert, James C., Thanassoulis, George
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2017
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833523/
https://ncbi.nlm.nih.gov/pubmed/29128868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamacardio.2017.4266
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