EZH2 inhibits autophagic cell death of aortic vascular smooth muscle cells to affect aortic dissection

Enhancer of zeste homolog 2 (EZH2), a methyltransferase that di- and tri-methylates lysine-27 of histone H3, largely functions as a transcriptional repressor, and plays a critical role in various kinds of cancers. Here we report a novel function of EZH2 in regulating autophagic cell death (ACD) of v...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Li, Rui, Yi, Xin, Wei, Xiang, Huo, Bo, Guo, Xian, Cheng, Cai, Fang, Ze-Min, Wang, Jing, Feng, Xin, Zheng, Ping, Su, Yun-Shu, Masau, Jackson Ferdinand, Zhu, Xue-Hai, Jiang, Ding-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833461/
https://ncbi.nlm.nih.gov/pubmed/29416002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0213-2
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