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Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling

Baicalin is a natural flavonoid glycoside which has potent anti-tumor and antioxidant activity in cancer cells. In the present study, we found that baicalin treatment significantly induced senescence in colon cancer cells. Furthermore, baicalin upregulated the expression of decidual protein induced...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Zhou, Ma, Lingman, Su, Mengqi, Zhou, Yiran, Mao, Ke, Li, Chengqin, Peng, Guangyong, Zhou, Changlin, Shen, Baiyong, Dou, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833439/
https://ncbi.nlm.nih.gov/pubmed/29440765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0223-0
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