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miR-663 sustains NSCLC by inhibiting mitochondrial outer membrane permeabilization (MOMP) through PUMA/BBC3 and BTG2

Treatment of lung cancer is an unmet need as it accounts for the majority of cancer deaths worldwide. The development of new therapies urges the identification of potential targets. MicroRNAs’ expression is often deregulated in cancer and their modulation has been proposed as a successful strategy t...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Fiori, Micol E., Villanova, Lidia, Barbini, Chiara, De Angelis, Maria Laura, De Maria, Ruggero
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833438/
https://ncbi.nlm.nih.gov/pubmed/29352138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0080-x
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