MicroRNA-27a-5p regulation by promoter methylation and MYC signaling in prostate carcinogenesis

Upregulation of MYC and miRNAs deregulation are common in prostate cancer (PCa). Overactive MYC may cause miRNAs’ expression deregulation through transcriptional and post-transcriptional mechanisms and epigenetic alterations are also involved in miRNAs dysregulation. Herein, we aimed to elucidate th...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Barros-Silva, Daniela, Costa-Pinheiro, Pedro, Duarte, Henrique, Sousa, Elsa Joana, Evangelista, Adriane Feijó, Graça, Inês, Carneiro, Isa, Martins, Ana Teresa, Oliveira, Jorge, Carvalho, André L., Marques, Márcia M., Henrique, Rui, Jerónimo, Carmen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833437/
https://ncbi.nlm.nih.gov/pubmed/29415999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0241-y
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