Induction of ER and mitochondrial stress by the alkylphosphocholine erufosine in oral squamous cell carcinoma cells

Endoplasmic reticulum (ER) plays an essential role in cell function and survival. Accumulation of unfolded or misfolded proteins in the lumen of the ER activates the unfolded protein response (UPR), resulting in ER stress and subsequent apoptosis. The alkylphosphocholine erufosine is a known Akt-mTO...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Ansari, Shariq S., Sharma, Ashwini K., Soni, Himanshu, Ali, Doaa M., Tews, Björn, König, Rainer, Eibl, Hansjörg, Berger, Martin R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833417/
https://ncbi.nlm.nih.gov/pubmed/29463797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0342-2
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