Primed atypical ductal hyperplasia-associated fibroblasts promote cell growth and polarity changes of transformed epithelium-like breast cancer MCF-7 cells via miR-200b/c-IKKβ signaling

Cancer-associated fibroblasts (CAFs) support tumorigenesis by stimulating cancer cell proliferation, and invasion, but how the premalignant stromal fibroblasts trigger epithelial changes remain unclear. We demonstrate that atypical ductal hyperplasia-associated fibroblasts (AHFs) are one kind of act...

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Publicat a:Cell Death Dis
Autors principals: Sun, Yan, Yang, Dan, Xi, Lei, Chen, Yanlin, Fu, Lixin, Sun, Kexin, Yin, Jiali, Li, Xiaotian, Liu, Shuiqing, Qin, Yilu, Liu, Manran, Hou, Yixuan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833401/
https://ncbi.nlm.nih.gov/pubmed/29374150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0133-1
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