14-3-3ζ delivered by hepatocellular carcinoma-derived exosomes impaired anti-tumor function of tumor-infiltrating T lymphocytes

Increasing evidence shows that the anti-tumor functions of tumor-infiltrating T lymphocytes (TILs) were inhibited significantly, but the underlying mechanisms remain not fully understood. In this study, we found that 14-3-3ζ expression was up-regulated in hepatocellular carcinoma (HCC) cells and in ...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Wang, Xiaochen, Shen, Haiyuan, Zhangyuan, Guangyan, Huang, Ruyi, Zhang, Wenjie, He, Qifeng, Jin, Kangpeng, Zhuo, Han, Zhang, Zechuan, Wang, Jincheng, Sun, Beicheng, Lu, Xiaojie
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833352/
https://ncbi.nlm.nih.gov/pubmed/29415983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0180-7
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