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Mixed lineage kinase ZAK promotes epithelial–mesenchymal transition in cancer progression

ZAK, a mixed lineage kinase, is often described as a positive or negative regulator of cell growth. We identified it as one of the top hits in our kinome cDNA screen for potent regulators of epithelial mesenchymal transition (EMT). Ectopic expression of ZAK promoted EMT phenotypes and apoptosis resi...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Li, Linna, Su, Ning, Zhou, Ting, Zheng, Dayong, Wang, Zheng, Chen, Haoyu, Yuan, Shoujun, Li, Wenliang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833348/
https://ncbi.nlm.nih.gov/pubmed/29396440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0161-x
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