Osteopontin promotes metastasis of intrahepatic cholangiocarcinoma through recruiting MAPK1 and mediating Ser675 phosphorylation of β-Catenin

The incidence and mortality of intrahepatic cholangiocarcinoma (ICC) are increasing worldwide in recent decades. Osteopontin (OPN) plays an important role in cancer metastasis, but its functional mechanism in ICC is not clear yet. In this study, we found that OPN level was elevated both in plasma an...

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Publicado en:Cell Death Dis
Main Authors: Zheng, Yan, Zhou, Chuang, Yu, Xin-Xin, Wu, Chao, Jia, Hu-Liang, Gao, Xiao-Mei, Yang, Ji-Meng, Wang, Chao-Qun, Luo, Qin, Zhu, Ying, Zhang, Yu, Wei, Jin-Wang, Sheng, Yuan-Yuan, Dong, Qiong-Zhu, Qin, Lun-Xiu
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833342/
https://ncbi.nlm.nih.gov/pubmed/29415992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0226-x
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