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Wolbachia-mediated virus blocking in mosquito cells is dependent on XRN1-mediated viral RNA degradation and influenced by viral replication rate

Wolbachia is currently being developed as a novel tool to block the transmission of dengue viruses (DENV) by Aedes aegypti. A number of mechanisms have been proposed to explain the DENV-blocking phenotype in mosquitoes, including competition for fatty acids like cholesterol, manipulation of host miR...

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Publicat a:PLoS Pathog
Autors principals: Thomas, Saijo, Verma, Jiyoti, Woolfit, Megan, O’Neill, Scott L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833283/
https://ncbi.nlm.nih.gov/pubmed/29494679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006879
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