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Genetic approaches to identify pathological limitations in aortic smooth muscle contraction
Aortic smooth muscle contains limiting amounts of myosin light chain kinase (MLCK) for myosin regulatory light chain (RLC) phosphorylation and contraction that predisposes to thoracic aortic disease in humans containing heterozygous loss-of-function mutations in MYLK. We tested the hypothesis that t...
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| Publié dans: | PLoS One |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5833278/ https://ncbi.nlm.nih.gov/pubmed/29494672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193769 |
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