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Using phase II data for the analysis of phase III studies: An application in rare diseases
BACKGROUND: Clinical research and drug development in orphan diseases are challenging, since large-scale randomized studies are difficult to conduct. Formally synthesizing the evidence is therefore of great value, yet this is rarely done in the drug-approval process. Phase III designs that make bett...
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| Publicat a: | Clin Trials |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
SAGE Publications
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5833035/ https://ncbi.nlm.nih.gov/pubmed/28387537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774517699409 |
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