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Hit Generation in TB Drug Discovery: From Genome to Granuloma

[Image: see text] Current tuberculosis (TB) drug development efforts are not sufficient to end the global TB epidemic. Recent efforts have focused on the development of whole-cell screening assays because biochemical, target-based inhibitor screens during the last two decades have not delivered new...

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Detalhes bibliográficos
Publicado no:Chem Rev
Main Authors: Yuan, Tianao, Sampson, Nicole S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832989/
https://ncbi.nlm.nih.gov/pubmed/29384369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.7b00602
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