p62/SQSTM1 promotes rapid ubiquitin conjugation to target proteins after endosome rupture during xenophagy

Autophagy is a bulk degradation pathway, and selective autophagy to remove foreign entities is called xenophagy. The conjugation of ubiquitin to target pathogens is an important process in xenophagy but when and where this ubiquitination occurs remains unclear. Here, we analyzed the temporal sequenc...

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Bibliografiske detaljer
Udgivet i:FEBS Open Bio
Main Authors: Tsuchiya, Megumi, Ogawa, Hidesato, Koujin, Takako, Mori, Chie, Osakada, Hiroko, Kobayashi, Shouhei, Hiraoka, Yasushi, Haraguchi, Tokuko
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832981/
https://ncbi.nlm.nih.gov/pubmed/29511624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12385
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