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Metabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs)

Fibroblasts can be directly reprogrammed to induced renal tubular epithelial cells (iRECs) using four transcription factors. These engineered cells may be used for disease modeling, cell replacement therapy or drug and toxicity testing. Direct reprogramming induces drastic changes in the transcripti...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lagies, Simon, Pichler, Roman, Kaminski, Michael M., Schlimpert, Manuel, Walz, Gerd, Lienkamp, Soeren S., Kammerer, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832874/
https://ncbi.nlm.nih.gov/pubmed/29497074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22073-7
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