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Lack of effects of simvastatin on smoking cessation in humans: A double-blind, randomized, placebo-controlled clinical study

A recent pre-clinical study has shown that brain-penetrating statins can reduce risks of relapse to cocaine and nicotine addiction in rats. Based on this information, we conducted a randomized, double-blind, placebo-controlled, proof-of-concept trial to assess the efficacy of simvastatin in smoking...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ingrand, Isabelle, Solinas, Marcello, Ingrand, Pierre, Dugast, Emilie, Saulnier, Pierre-Jean, Pérault-Pochat, Marie-Christine, Lafay-Chebassier, Claire
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832803/
https://ncbi.nlm.nih.gov/pubmed/29497063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21819-7
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