Dioscin inhibits stem-cell-like properties and tumor growth of osteosarcoma through Akt/GSK3/β-catenin signaling pathway

Osteosarcoma is the most common primary bone tumor in children and adolescents. Many patients with osteosarcoma always develop drug resistance to current chemotherapy regimens, which induces a poor prognosis. And cancer stem cells (CSCs) have been reported to possess the properties to self-renew and...

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Опубликовано в: :Cell Death Dis
Главные авторы: Liu, Weihai, Zhao, Zhiqiang, Wang, Yongqian, Li, Wuguo, Su, Qiao, Jia, Qiang, Zhang, Jiajun, Zhang, Xuelin, Shen, Jingnan, Yin, Junqiang
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832770/
https://ncbi.nlm.nih.gov/pubmed/29497056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0363-x
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