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Engineering Axl specific CAR and SynNotch receptor for cancer therapy
Axl is a tyrosine kinase receptor that is commonly overexpressed in many cancers. As such, Axl represents an attractive therapeutic target. The transfer of engineered T cell expressing chimeric antigen receptor (CAR) is an exciting cancer therapeutic approach that shows high efficacy against cancers...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5832765/ https://ncbi.nlm.nih.gov/pubmed/29497107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22252-6 |
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