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Fibroblast Growth Factor 21 increases hepatic oxidative capacity but not physical activity or energy expenditure in hepatic PGC-1α deficient mice
Fibroblast growth factor 21 (FGF21) treatment drives metabolic improvements, including increased metabolic flux and reduced hepatic steatosis, but mechanisms responsible for these effects remain to be fully elucidated. We tested if a targeted reduction in hepatic PGC-1α, which has been shown to occu...
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| Publicado no: | Exp Physiol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5832578/ https://ncbi.nlm.nih.gov/pubmed/29215172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/EP086629 |
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