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Overproduction of Sch9 leads to its aggregation and cell elongation in Saccharomyces cerevisiae

The Sch9 kinase of Saccharomyces cerevisiae is one of the major TOR pathway effectors and regulates diverse processes in the cell. Sch9 belongs to the AGC kinase family. In human, amplification of AGC kinase genes is connected with cancer. However, not much is known about the effects of Sch9 overpro...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Drozdova, Polina, Lipaeva, Polina, Rogoza, Tatyana, Zhouravleva, Galina, Bondarev, Stanislav
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832320/
https://ncbi.nlm.nih.gov/pubmed/29494682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193726
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