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MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo

There is a high quest for novel therapeutic strategies to enhance recovery after stroke. MicroRNA-124 (miR-124) has been described as neuroprotective and anti-inflammatory molecule. Moreover, miR-124 is a well described enhancer of adult neurogenesis that could offer potentially beneficial effects....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Saraiva, Cláudia, Talhada, Daniela, Rai, Akhilesh, Ferreira, Raquel, Ferreira, Lino, Bernardino, Liliana, Ruscher, Karsten
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832317/
https://ncbi.nlm.nih.gov/pubmed/29494665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193609
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