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Combined effect of glutamine at position 70 of HLA-DRB1 and alanine at position 57 of HLA-DQB1 in type 1 diabetes: An epitope analysis

The contribution of specific HLA Class II alleles in type 1 diabetes is determined by polymorphic amino acid epitopes that direct antigen binding therefore, along with conventional allele frequency analysis, epitope analysis can provide important insights into disease susceptibility. We analyzed the...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Gerasimou, Petroula, Nicolaidou, Vicky, Skordis, Nicos, Picolos, Michalis, Monos, Demetrios, Costeas, Paul A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832312/
https://ncbi.nlm.nih.gov/pubmed/29494662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193684
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