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Opposite effect of polyamines on In vitro gene expression: Enhancement at low concentrations but inhibition at high concentrations

BACKGROUND: Polyamines have various biological functions including marked effects on the structure and function of genomic DNA molecules. Changes in the higher-order structure of DNA caused by polyamines are expected to be closely related to genetic activity. To clarify this issue, we examined the r...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kanemura, Ai, Yoshikawa, Yuko, Fukuda, Wakao, Tsumoto, Kanta, Kenmotsu, Takahiro, Yoshikawa, Kenichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832264/
https://ncbi.nlm.nih.gov/pubmed/29494707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193595
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