Flavanones from Sedum sarmentosum Bunge Alleviate CCl(4)-Induced Liver Fibrosis in Rats by Targeting TGF-β1/TβR/Smad Pathway In Turn Inhibiting Epithelial Mesenchymal Transition

OBJECTIVE: The aim of the study is to evaluate the therapeutic effects of flavanones from Sedum sarmentosum Bunge (FSSB) on CCl(4)-induced liver fibrosis in rats and the underlying mechanisms of action. METHODS: An experimental model of liver fibrosis was established by subcutaneous injection of rat...

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Pubblicato in:Evid Based Complement Alternat Med
Autori principali: Lin, Yuancan, Luo, Haiying, Wang, Xiao, Zheng, Minxia, Jin, Qianxing, Chen, Hongshu, Pan, Peilei, Zhang, Junjie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832160/
https://ncbi.nlm.nih.gov/pubmed/29636774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3080837
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