Gut Microbes Egested During Bites of Infected Sand flies Augment Severity of Leishmaniasis Via Inflammasome-Derived IL-1β

Leishmania donovani parasites are the cause of visceral leishmaniasis, and are transmitted by bite from phlebotomine sand flies. A prominent feature of vector-transmitted Leishmania is the persistence of neutrophils at bite sites, where they protect captured parasites leading to enhanced disease. He...

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Veröffentlicht in:Cell Host Microbe
Hauptverfasser: Dey, Ranadhir, Joshi, Amritanshu B., Oliveira, Fabiano, Pereira, Lais, Guimarães-Costa, Anderson B., Serafim, Tiago D., de Castro, Waldionê, Coutinho-Abreu, Iliano V., Bhattacharya, Parna, Townsend, Shannon, Aslan, Hamide, Perkins, Alec, Karmakar, Subir, Ismail, Nevien, Karetnick, Morgan, Meneses, Claudio, Duncan, Robert, Nakhasi, Hira L., Valenzuela, Jesus G., Kamhawi, Shaden
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832060/
https://ncbi.nlm.nih.gov/pubmed/29290574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.12.002
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