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Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer’s disease

Although the genetic causes for several rare, familial forms of Alzheimer’s disease (AD) have been identified, the etiology of the sporadic form of AD remains unclear. Here, we report a systems-level study of disease-associated proteome changes in human frontal cortex of sporadic AD patients using a...

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Dettagli Bibliografici
Pubblicato in:Acta Neuropathol Commun
Autori principali: Zhang, Qi, Ma, Cheng, Gearing, Marla, Wang, Peng George, Chin, Lih-Shen, Li, Lian
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831854/
https://ncbi.nlm.nih.gov/pubmed/29490708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0524-2
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