Prediction of GPCR-Ligand Binding Using Machine Learning Algorithms

We propose a novel method that predicts binding of G-protein coupled receptors (GPCRs) and ligands. The proposed method uses hub and cycle structures of ligands and amino acid motif sequences of GPCRs, rather than the 3D structure of a receptor or similarity of receptors or ligands. The experimental...

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Bibliografiska uppgifter
I publikationen:Comput Math Methods Med
Huvudupphovsmän: Seo, Sangmin, Choi, Jonghwan, Ahn, Soon Kil, Kim, Kil Won, Kim, Jaekwang, Choi, Jaehyuck, Kim, Jinho, Ahn, Jaegyoon
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831789/
https://ncbi.nlm.nih.gov/pubmed/29666662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/6565241
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