Therapeutic and pharmaco-biological, dose-ranging multicentre trial to determine the optimal dose of TRAnexamic acid to reduce blood loss in haemorrhagic CESarean delivery (TRACES): study protocol for a randomised, double-blind, placebo-controlled trial

BACKGROUND: Postpartum haemorrhage (PPH) is the leading cause of maternal death worldwide. Tranexamic acid (TA), an antifibrinolytic drug, reduces bleeding and transfusion need in major surgery and trauma. In ongoing PPH following vaginal delivery, a high dose of TA decreases PPH volume and duration...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Bouthors, Anne-Sophie, Hennart, Benjamin, Jeanpierre, Emmanuelle, Baptiste, Anne-Sophie, Saidi, Imen, Simon, Elodie, Lannoy, Damien, Duhamel, Alain, Allorge, Delphine, Susen, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831710/
https://ncbi.nlm.nih.gov/pubmed/29490682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-017-2420-7
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