Oil Palm Phenolics Inhibit the In Vitro Aggregation of β-Amyloid Peptide into Oligomeric Complexes

Alzheimer's disease is a severe neurodegenerative disease characterized by the aggregation of amyloid-β peptide (Aβ) into toxic oligomers which activate microglia and astrocytes causing acute neuroinflammation. Multiple studies show that the soluble oligomers of Aβ42 are neurotoxic and proinfla...

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Detalhes bibliográficos
Publicado no:Int J Alzheimers Dis
Main Authors: Weinberg, Robert P., Koledova, Vera V., Shin, Hyeari, Park, Jennifer H., Tan, Yew Ai, Sinskey, Anthony J., Sambanthamurthi, Ravigadevi, Rha, ChoKyun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831689/
https://ncbi.nlm.nih.gov/pubmed/29666700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7608038
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