The Relationship between TP53 Gene Status and Carboxylesterase 2 Expression in Human Colorectal Cancer

Irinotecan (CPT-11) is an anticancer prodrug that is activated by the carboxylesterase CES2 and has been approved for the treatment of many types of solid tumors, including colorectal cancer. Recent studies with cell lines show that CES2 expression is regulated by the tumor suppressor protein p53. H...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Dis Markers
Main Authors: Ishimine, Momoko, Lee, Hyeon-Cheol, Nakaoka, Hirofumi, Orita, Hajime, Kobayashi, Toshiyuki, Mizuguchi, Konomi, Endo, Mikumi, Inoue, Ituro, Sato, Koichi, Yokomizo, Takehiko
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831679/
https://ncbi.nlm.nih.gov/pubmed/29651325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/5280736
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados