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TNF-α-mediated reduction in PGC1-α may impair skeletal muscle function after cigarette smoke exposure
Skeletal muscle dysfunction contributes to exercise limitation in COPD. In this study cigarette smoke exposure was hypothesized to increase expression of the inflammatory cytokine, TNF-α, and down stream molecules that regulate oxygen transport and muscle function. Furthermore, we hypothesized that...
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| Publicado no: | J Cell Physiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5831677/ https://ncbi.nlm.nih.gov/pubmed/19859910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21955 |
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