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CARTILAGE OLIGOMERIC MATRIX PROTEIN PARTICIPATES IN THE PATHOGENESIS OF LIVER FIBROSIS

BACKGROUND & AIMS: Liver fibrosis is characterized by significant accumulation of extracellular matrix (ECM) proteins, mainly fibrillar collagen-I, as a result of persistent liver injury. Cartilage oligomeric matrix protein (COMP) is largely found in the ECM of skeletal tissue. Increased COMP ex...

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Bibliographic Details
Published in:J Hepatol
Main Authors: Magdaleno, Fernando, Arriazu, Elena, de Galarreta, Marina Ruiz, Chen, Yu, Ge, Xiaodong, de la Rosa, Laura Conde, Nieto, Natalia
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831373/
https://ncbi.nlm.nih.gov/pubmed/27318326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2016.06.003
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