Transitional basal cells at the squamous-columnar junction generate Barrett’s oesophagus

In several organ systems the transitional zone between different types of epithelia is a hotspot for pre-neoplastic metaplasia and malignancy(1–3). However, the cell-of-origin for the metaplastic epithelium and subsequent malignancy, remains obscure(1–3). In the case of Barrett’s oesophagus (BE), in...

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Vydáno v:Nature
Hlavní autoři: Jiang, Ming, Li, Haiyan, Zhang, Yongchun, Yang, Ying, Lu, Rong, Liu, Kuancan, Lin, Sijie, Lan, Xiaopeng, Wang, Haikun, Wu, Han, Zhu, Jian, Zhou, Zhongren, Xu, Jianming, Lee, Dong-Kee, Zhang, Lanjing, Lee, Yuan-Cho, Yuan, Jingsong, Abrams, Julian A., Wang, Timothy G., Sepulveda, Antonia R., Wu, Qi, Chen, Huaiyong, Sun, Xin, She, Junjun, Chen, Xiaoxin, Que, Jianwen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831195/
https://ncbi.nlm.nih.gov/pubmed/29019984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24269
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