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Understanding the correlation between in vitro and in vivo immunotoxicity tests for nanomedicines

Preclinical characterization of novel nanotechnology-based formulations is often challenged by physicochemical characteristics, sterility/sterilization issues, safety and efficacy. Such challenges are not unique to nanomedicine, as they are common in the development of small and macromolecular drugs...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Control Release
Hauptverfasser: Dobrovolskaia, Marina A., McNeil, Scott E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5831149/
https://ncbi.nlm.nih.gov/pubmed/23742883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.05.025
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