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Subcellular distribution of ERK phosphorylation in tyrosine and threonine depends on redox status in murine lung cells
Activation of ERK1/2 implies the phosphorylation of tyrosine (pTyr) and threonine (pThr) by MEK1/2; both reactions were thought to be cytoplasmic, promoting ERK to reach the nucleus where it activates several transcription factors. In addition, H(2)O(2) concentrations are known to modulate ERK intra...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5831038/ https://ncbi.nlm.nih.gov/pubmed/29489891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193022 |
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