Laser Capture and Deep Sequencing Reveals the Transcriptomic Programmes Regulating the Onset of Pancreas and Liver Differentiation in Human Embryos

To interrogate the alternative fates of pancreas and liver in the earliest stages of human organogenesis, we developed laser capture, RNA amplification, and computational analysis of deep sequencing. Pancreas-enriched gene expression was less conserved between human and mouse than for liver. The dor...

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Pubblicato in:Stem Cell Reports
Autori principali: Jennings, Rachel E., Berry, Andrew A., Gerrard, David T., Wearne, Stephen J., Strutt, James, Withey, Sarah, Chhatriwala, Mariya, Piper Hanley, Karen, Vallier, Ludovic, Bobola, Nicoletta, Hanley, Neil A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
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Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830993/
https://ncbi.nlm.nih.gov/pubmed/29056335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.09.018
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