Adult mouse eIF2Bε Arg191His astrocytes display a normal integrated stress response in vitro

Vanishing white matter (VWM) is a genetic childhood white matter disorder, characterized by chronic as well as episodic, stress provoked, neurological deterioration. Treatment is unavailable and patients often die within a few years after onset. VWM is caused by recessive mutations in the eukaryotic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wisse, Lisanne E., ter Braak, Timo J., van de Beek, Malu-Clair, van Berkel, Carola G. M., Wortel, Joke, Heine, Vivi M., Proud, Chris G., van der Knaap, Marjo S., Abbink, Truus E. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830650/
https://ncbi.nlm.nih.gov/pubmed/29491431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21885-x
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