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Repeated Morphine Produces Sensitization to Reward and Tolerance to Antiallodynia in Male and Female Rats with Chemotherapy-Induced Neuropathy

Paclitaxel is a cancer chemotherapy drug with adverse effects that include chemotherapy-induced neuropathic pain (CINP) as well as depression of behavior and mood. In the clinical setting, opioids are often used concurrently with or after chemotherapy to treat pain related to the cancer or CINP, but...

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Détails bibliographiques
Publié dans:J Pharmacol Exp Ther
Auteurs principaux: Legakis, L. P., Negus, S. S.
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830638/
https://ncbi.nlm.nih.gov/pubmed/29363579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.246215
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