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A novel Epstein–Barr virus-latent membrane protein-1-specific T-cell receptor for TCR gene therapy

BACKGROUND: Adoptive transfer of genetically engineered T-cells to express antigen-specific T-cell receptor (TCR) is a feasible and effective therapeutic approach for numerous types of cancers, including Epstein–Barr virus (EBV)-associated malignancies. Here, we describe a TCR gene transfer regimen...

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Publicat a:Br J Cancer
Autors principals: Cho, Hyun-Il, Kim, Un-Hee, Shin, A-Ri, Won, Ji-Na, Lee, Hyun-Joo, Sohn, Hyun-Jung, Kim, Tai-Gyu
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830600/
https://ncbi.nlm.nih.gov/pubmed/29360818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.475
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