H1/pHGFK1 nanoparticles exert anti-tumoural and radiosensitising effects by inhibition of MET in glioblastoma

BACKGROUND: The therapeutic resistance to ionising radiation (IR) and anti-angiogenesis mainly impair the prognosis of patients with glioblastoma. The primary and secondary MET aberrant activation is one crucial factor for these resistances. The kringle 1 domain of hepatocyte growth factor (HGFK1),...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Zhang, Wenyan, Duan, Rui, Zhang, Jian, Cheung, William K C, Gao, Xiaoge, Zhang, Raymond, Zhang, Qing, Wei, Mengxue, Wang, Gang, Zhang, Qian, Mei, Peng-jin, Chen, Hong-lin, Kung, Hsiangfu, Lin, Marie C, Shen, Zan, Zheng, Junnian, Zhang, Longzhen, Yao, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830599/
https://ncbi.nlm.nih.gov/pubmed/29348487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.461
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