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Myocardial polyploidization creates a barrier to heart regeneration in zebrafish
Correlative evidence suggests that polyploidization of heart muscle, which occurs naturally in post-natal mammals, creates a barrier to heart regeneration. Here, we move beyond a correlation by demonstrating that experimental polyploidization of zebrafish cardiomyocytes is sufficient to suppress the...
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| Publié dans: | Dev Cell |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5830170/ https://ncbi.nlm.nih.gov/pubmed/29486195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.01.021 |
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