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Transient transcriptional silencing alters the cell cycle to promote germline stem cell differentiation in Drosophila

Transcriptional silencing is a conserved process used by embryonic germ cells to repress somatic fate and maintain totipotency and immortality. In Drosophila, this transcriptional silencing is mediated by polar granule component (pgc). Here, we show that in the adult ovary, pgc is required for timel...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Flora, Pooja, Schowalter, Sean, Wong-Deyrup, SiuWah, DeGennaro, Matthew, Nasrallah, Mohamad Ali, Rangan, Prashanth
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830152/
https://ncbi.nlm.nih.gov/pubmed/29198563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2017.11.014
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