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Transient transcriptional silencing alters the cell cycle to promote germline stem cell differentiation in Drosophila

Transcriptional silencing is a conserved process used by embryonic germ cells to repress somatic fate and maintain totipotency and immortality. In Drosophila, this transcriptional silencing is mediated by polar granule component (pgc). Here, we show that in the adult ovary, pgc is required for timel...

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Bibliografski detalji
Izdano u:Dev Biol
Glavni autori: Flora, Pooja, Schowalter, Sean, Wong-Deyrup, SiuWah, DeGennaro, Matthew, Nasrallah, Mohamad Ali, Rangan, Prashanth
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830152/
https://ncbi.nlm.nih.gov/pubmed/29198563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2017.11.014
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