Class-modeling analysis reveals T-cell homeostasis disturbances involved in loss of immune control in elite controllers

BACKGROUND: Despite long-lasting HIV replication control, a significant proportion of elite controller (EC) patients may experience CD4 T-cell loss. Discovering perturbations in immunological parameters could help our understanding of the mechanisms that may be operating in those patients experienci...

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Vydáno v:BMC Med
Hlavní autoři: Benito, José M., Ortiz, María C., León, Agathe, Sarabia, Luis A., Ligos, José M., Montoya, María, Garcia, Marcial, Ruiz-Mateos, Ezequiel, Palacios, Rosario, Cabello, Alfonso, Restrepo, Clara, Rodriguez, Carmen, del Romero, Jorge, Leal, Manuel, Muñoz-Fernández, María A., Alcamí, José, García, Felipe, Górgolas, Miguel, Rallón, Norma
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830067/
https://ncbi.nlm.nih.gov/pubmed/29490663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-018-1026-6
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