Proximity of Cytomegalovirus-Specific CD8(+) T Cells to Replicative Senescence in Human Immunodeficiency Virus-Infected Individuals

Antiretroviral therapy (ART) effectively extends the life expectancy of human immunodeficiency virus (HIV)-infected individuals; however, age-related morbidities have emerged as major clinical concerns. In this context, coinfection with cytomegalovirus (CMV) accelerates immune senescence and elevate...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Heath, John Joseph, Fudge, Neva Jennifer, Gallant, Maureen Elizabeth, Grant, Michael David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829617/
https://ncbi.nlm.nih.gov/pubmed/29527205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00201
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